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Mutagenesis vol. 1 no. 5 pp. 343-346, 1986
© 1986 UK Environmental Mutagen Society/Oxford University Press

other

Mutagenicity testing of the pyrethroid insecticide cypermethrin in Drosophila

M. Batiste-Alentorn, N. Xamena, A. Velázquez, A. Creus and R. Marcos1

Divisió de Genètica, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona Bellaterra, Spain

The pyrethroid insecticide cypermethrin was tested for the induction of genetic damage in male germ cells of Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and non-disjunction were studied following different routes of administration: adult feeding, injection and larval feeding. Our results show that, after adult injection and larval ingest ion, cypermethrin induces a small but significant increase in the frequency of sex-linked recessive lethal mutations. However, no significant increases were observed in the frequency of sex chromosome loss or non-disjunction after exposure of male flies to cypermethrin at concentrations up to 20 p.p.m.

1To whom correspondence should be addressed


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S. Giri, A. Giri, G. D. Sharma, and S. B. Prasad
Induction of sister chromatid exchanges by cypermethrin and carbosulfan in bone marrow cells of mice in vivo
Mutagenesis, January 1, 2003; 18(1): 53 - 58.
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