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Mutagenesis, Vol. 18, No. 3, 311-317, May 2003
© 2003 UK Environmental Mutagen Society/Oxford University Press

MEETING REPORT

Report of a symposium on the use of genomics and proteomics in toxicology*

T. Barlow, J. Battershill1, B.R. Jeffery, F.D. Pollitt1 and C.S.M. Tahourdin2

Chemical Safety and Toxicology Division, Food Standards Agency, Aviation House, 125 Kingsway, London WC2B 6NH, UK and 1 Department of Health, Skipton House, 80 London Road, Elephant and Castle, London SE1 6LH, UK

The first 150 words of the full text of this article appear below.

Over the past few years, and especially since publication of the sequence of the human genome (International Human Genome Sequencing Consortium, 2001Go), there has been increasing pressure to incorporate novel technologies such as proteomics and genomics into toxicological risk assessment.

The Committee on Toxicity of Chemicals in Food, Consumer Products and the Environment (COT) and its sister Committees on Carcinogenicity and Mutagenicity (COC and COM) held a symposium to consider this issue on 8 October 2001 at Skipton House, Elephant and Castle, London, UK. The meeting was attended by members of COT, COC and COM and also included members of the Advisory Committee on Hazardous Substances, the Advisory Committee on Pesticides, invited speakers from academia and industry and delegates from various Government Departments. It was also open to anyone with an interest in this area.

COT, COC and COM are independent expert advisory committees appointed by the Chief Medical . . . [Full Text of this Article]

Introductory session

Overview of use of genomics and proteomics in toxicology
Genomics
Proteomics
Risk assessment
Working Group sessions

Use of genomics (transcript profiling) in screening
Applications of proteomics in toxicology
Use of genomics/proteomics in risk assessment
Discussion session

Genomics
Proteomics
Risk assessment

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[Abstract] [PDF]