Mutagenesis

COMMENTARY:

John A. Heddle

Mutant manifestation: the time factor in somatic mutagenesis
Mutagenesis 1999 14: 1-3; doi:10.1093/mutage/14.1.1 [Extract] [Full Text] [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

Masamitsu Honma, Makoto Hayashi, Hiroyasu Shimada, Noriho Tanaka, Shinobu Wakuri, Takumi Awogi, Koichi I. Yamamoto, Noriko-Ushio Kodani, Yoshisuke Nishi, Masahiro Nakadate, and Toshio Sofuni

Evaluation of the mouse lymphoma tk assay (microwell method) as an alternative to the in vitro chromosomal aberration test
Mutagenesis 1999 14: 5-22; doi:10.1093/mutage/14.1.5 [Abstract] [Full Text] [PDF] [Request Permissions]  

Masamitsu Honma, Li-Shi Zhang, Hiroko Sakamoto, Masayasu Ozaki, Kenji Takeshita, Maki Momose, Makoto Hayashi, and Toshio Sofuni

The need for long-term treatment in the mouse lymphoma assay
Mutagenesis 1999 14: 23-29; doi:10.1093/mutage/14.1.23 [Abstract] [Full Text] [PDF] [Request Permissions]  

Jyh Chang Jean, Cary O. Harding, Sean M. Oakes, Qiang Yu, Patrice K. Held, and Martin Joyce-Brady

-Glutamyl transferase (GGT) deficiency in the GGT^enu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA
Mutagenesis 1999 14: 31-36; doi:10.1093/mutage/14.1.31 [Abstract] [Full Text] [PDF] [Request Permissions]  

Gareth J.S. Jenkins, Nobuo Takahashi, and James M. Parry

Inverse restriction site mutation (iRSM) analysis. Mutation detection involving the formation of restriction enzyme sites in target genes
Mutagenesis 1999 14: 37-42; doi:10.1093/mutage/14.1.37 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sandra Minissi, Bianca Gustavino, Francesca Degrassi, Caterina Tanzarella, and Marco Rizzoni

Effect of cytochalasin B on the induction of chromosome missegregation by colchicine at low concentrations in human lymphocytes
Mutagenesis 1999 14: 43-49; doi:10.1093/mutage/14.1.43 [Abstract] [Full Text] [PDF] [Request Permissions]  

M. Schuler, P. Muehlbauer, P. Guzzie, and D.A. Eastmond

Noscapine hydrochloride disrupts the mitotic spindle in mammalian cells and induces aneuploidy as well as polyploidy in cultured human lymphocytes
Mutagenesis 1999 14: 51-56; doi:10.1093/mutage/14.1.51 [Abstract] [Full Text] [PDF] [Request Permissions]  

S. Simi, Y. Xiao, M. Campagna, J. Doehmer, and F. Darroudi

Dual-colour FISH analysis to characterize a marker chromosome in cytochrome P450 2B1 recombinant V79 Chinese hamster cells
Mutagenesis 1999 14: 57-61; doi:10.1093/mutage/14.1.57 [Abstract] [Full Text] [PDF] [Request Permissions]  

Marcela González-Cid, María Teresa Cuello, and Irene Larripa

Comparison of the aneugenic effect of vinorelbine and vincristine in cultured human lymphocytes
Mutagenesis 1999 14: 63-66; doi:10.1093/mutage/14.1.63 [Abstract] [Full Text] [PDF] [Request Permissions]  

Ünal Egeli, Nilüfer Aydemir, Gürler Akpinar, Ciigdem Ciimen, Emel Ergül, Gülsiah Tutar, Berrin Tunca, and Rahmi Bilaloglu

In vivo dominant lethal effect of pyrimethamine in male mouse germ cells
Mutagenesis 1999 14: 67-69; doi:10.1093/mutage/14.1.67 [Abstract] [Full Text] [PDF] [Request Permissions]  

Ciara M.Hughes, Valerie J.McKelvey-Martin, and Sheena E.M. Lewis

Human sperm DNA integrity assessed by the Comet and ELISA assays
Mutagenesis 1999 14: 71-75; doi:10.1093/mutage/14.1.71 [Abstract] [Full Text] [PDF] [Request Permissions]  

Massimo Bogliolo, Alberto Izzotti, Silvio De Flora, Carla Carli, Angelo Abbondandolo, and Paolo Degan

Detection of the `4977 bp' mitochondrial DNA deletion in human atherosclerotic lesions
Mutagenesis 1999 14: 77-82; doi:10.1093/mutage/14.1.77 [Abstract] [Full Text] [PDF] [Request Permissions]  

Nicolai N. Ilyinskikh, Irina N. Ilyinskikh, and Ekaterina N. Ilyinskikh

Chromosome breakage at sites of oncogenes in a population accidentally exposed to radioactive chemical pollution
Mutagenesis 1999 14: 83-86; doi:10.1093/mutage/14.1.83 [Abstract] [Full Text] [PDF] [Request Permissions]  

Jacqueline Cloos, Colin B.A. Reid, Marianne L.T. van der Sterre, Hilde Tobi, Charles R. Leemans, Gordon B. Snow, and Boudewijn J.M. Braakhuis

A comparison of bleomycin-induced damage in lymphocytes and primary oral fibroblasts and keratinocytes in 30 subjects
Mutagenesis 1999 14: 87-93; doi:10.1093/mutage/14.1.87 [Abstract] [Full Text] [PDF] [Request Permissions]  

Julia Ruiz-Laguna and Carmen Pueyo

Hydrogen peroxide and coffee induce G:CT:A transversions in the lacI gene of catalase-defective Escherichia coli
Mutagenesis 1999 14: 95-102; doi:10.1093/mutage/14.1.95 [Abstract] [Full Text] [PDF] [Request Permissions]  

Pasquale Mosesso, Enrica Fonti, Loredana Bassi, Claudia Lorenti Garcia, and Fabrizio Palitti

The involvement of chromatin condensation in camptothecin-induced chromosome breaks in G₀ human lymphocytes
Mutagenesis 1999 14: 103-105; doi:10.1093/mutage/14.1.103 [Abstract] [Full Text] [PDF] [Request Permissions]  

R. De Salvia, M. Fiore, T. Aglitti, F. Festa, R. Ricordy, and R. Cozzi

Inhibitory action of melatonin on H₂O₂- and cyclophosphamide-induced DNA damage
Mutagenesis 1999 14: 107-112; doi:10.1093/mutage/14.1.107 [Abstract] [Full Text] [PDF] [Request Permissions]  

Lidia Cosentino and John A. Heddle

A comparison of the effects of diverse mutagens at the lacZ transgene and Dlb-1 locus in vivo
Mutagenesis 1999 14: 113-119; doi:10.1093/mutage/14.1.113 [Abstract] [Full Text] [PDF] [Request Permissions]  

M.J. Ramírez, J. Surrallés, P. Galofré, A. Creus, and R. Marcos

FISH analysis of 1cen–1q12 breakage, chromosome 1 numerical abnormalities and centromeric content of micronuclei in buccal cells from thyroid cancer and hyperthyroidism patients treated with radioactive iodine
Mutagenesis 1999 14: 121-127; doi:10.1093/mutage/14.1.121 [Abstract] [Full Text] [PDF] [Request Permissions]  

Anna Wójcik and Celina Janion

Effect of Tn10/Tn5 transposons on the survival and mutation frequency of halogen light-irradiated AB1157 Escherichia coli K-12
Mutagenesis 1999 14: 129-134; doi:10.1093/mutage/14.1.129 [Abstract] [Full Text] [PDF] [Request Permissions]  

Philip C. Burcham and Louise A. Harkin

Mutations at G:C base pairs predominate after replication of peroxyl radical-damaged pSP189 plasmids in human cells
Mutagenesis 1999 14: 135-140; doi:10.1093/mutage/14.1.135 [Abstract] [Full Text] [PDF] [Request Permissions]  

REVIEWS:

S.W. Dean, T.M. Brooks, B. Burlinson, J. Mirsalis, B. Myhr, L. Recio, and V. Thybaud

Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens
Mutagenesis 1999 14: 141-151; doi:10.1093/mutage/14.1.141 [Abstract] [Full Text] [PDF] [Request Permissions]  

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