Mutagenesis

EDITORIAL:

James M. Parry

Applications and interpretation of data obtained in the mouse lymphoma tk assay
Mutagenesis 1999 14: 255; doi:10.1093/mutage/14.3.255 [Extract] [Full Text] [PDF] [Request Permissions]  

DISCUSSION FORUM:

John A. Heddle

On clonal expansion and its effects on mutant frequencies, mutation spectra and statistics for somatic mutations in vivo
Mutagenesis 1999 14: 257-260; doi:10.1093/mutage/14.3.257 [Extract] [Full Text] [PDF] [Request Permissions]  

Martha M. Moore, Deborah D. Collard, and Karen Harrington-Brock

Failure to adequately use positive control data leads to poor quality mouse lymphoma data assessments
Mutagenesis 1999 14: 261-263; doi:10.1093/mutage/14.3.261 [Extract] [Full Text] [PDF] [Request Permissions]  

Jane Cole, Karen Harrington-Brock, and Martha M. Moore

The mouse lymphoma assay in the wake of ICH4—where are we now?
Mutagenesis 1999 14: 265-270; doi:10.1093/mutage/14.3.265 [Extract] [Full Text] [PDF] [Request Permissions]  

REVIEWS:

Martha M. Moore, Karen Harrington-Brock, and Jane Cole

Issues for conducting the microtiter version of the mouse lymphoma thymidine kinase (tk) assay and a critical review of data generated in a collaborative trial using the microtiter method
Mutagenesis 1999 14: 271-281; doi:10.1093/mutage/14.3.271 [Extract] [Full Text] [PDF] [Request Permissions]  

ORIGINAL ARTICLES:

S. Chatterjee, W. Martínez-López, M. Grigorova, F. Darroudi, G. Obe, and A.T. Natarajan

Comparison of AluI-induced frequencies of dicentrics and translocations in human lymphocytes by chromosome painting
Mutagenesis 1999 14: 283-286; doi:10.1093/mutage/14.3.283 [Abstract] [Full Text] [PDF] [Request Permissions]  

Martijn E.T. Dollé, Hans-Jörg Martus, Maja Novak, Nathalie J. van Orsouw, and Jan Vijg

Characterization of color mutants in lacZ plasmid-based transgenic mice, as detected by positive selection
Mutagenesis 1999 14: 287-293; doi:10.1093/mutage/14.3.287 [Abstract] [Full Text] [PDF] [Request Permissions]  

Magdalena Felczak, Anna Bebenek, and Irena Pietrzykowska

The isfA mutation specifically inhibits the SOS-dependent mutagenic pathway and does not selectively affect any particular base substitution
Mutagenesis 1999 14: 295-300; doi:10.1093/mutage/14.3.295 [Abstract] [Full Text] [PDF] [Request Permissions]  

D.H. Phillips and M. Castegnaro

Standardization and validation of DNA adduct postlabelling methods: report of interlaboratory trials and production of recommended protocols
Mutagenesis 1999 14: 301-315; doi:10.1093/mutage/14.3.301 [Abstract] [Full Text] [PDF] [Request Permissions]  

Sandra A.M. Bol, Harry van Steeg, Conny Th.M. van Oostrom, Ad D. Tates, Harry Vrieling, Anton J.L. de Groot, Leon H.F. Mullenders, Albert A. van Zeeland, and Jacob G. Jansen

Nucleotide excision repair modulates the cytotoxic and mutagenic effects of N-n-butyl-N-nitrosourea in cultured mammalian cells as well as in mouse splenocytes in vivo
Mutagenesis 1999 14: 317-322; doi:10.1093/mutage/14.3.317 [Abstract] [Full Text] [PDF] [Request Permissions]  

S.García Franco, G. Domínguez, and J.C. Pico

Alternatives in the induction and preparation of phenobarbital/naphthoflavone-induced S9 and their activation profiles
Mutagenesis 1999 14: 323-326; doi:10.1093/mutage/14.3.323 [Abstract] [Full Text] [PDF] [Request Permissions]  

Anna Renglin, Ann-Sofi Härmälä-Brasken, John E. Eriksson, and Agneta Önfelt

Mitotic aberrations induced by carbaryl reflect tyrosine kinase inhibition with coincident up-regulation of serine/threonine protein phosphatase activity: implications for coordination of karyokinesis and cytokinesis
Mutagenesis 1999 14: 327-333; doi:10.1093/mutage/14.3.327 [Abstract] [Full Text] [PDF] [Request Permissions]  

Siobhán Higgins, M. Helena Vasconcelos, and Nora M.O'Brien

Effects of oleic acid, docosahexaenoic acid and eicosapentaenoic acid on background and genotoxin-induced frequencies of SCEs in Indian muntjac fibroblasts
Mutagenesis 1999 14: 335-338; doi:10.1093/mutage/14.3.335 [Abstract] [Full Text] [PDF] [Request Permissions]  

Brian J. Glassner, Geert Weeda, James M. Allan, Jose' L.M. Broekhof, Nick H.E. Carls, Ingrid Donker, Bevin P. Engelward, Richard J. Hampson, Remko Hersmus, Mark J. Hickman, Richard B. Roth, Henry B. Warren, Mavis M. Wu, Jan H.J. Hoeijmakers, and Leona D. Samson

DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents
Mutagenesis 1999 14: 339-347; doi:10.1093/mutage/14.3.339 [Abstract] [Full Text] [PDF] [Request Permissions]  

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